ST6GAL1 antibody
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Description
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ST6 beta-galactosamide alpha-2, 6-sialyltranferase 1 (ST6GAL1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P15907 |
| Gene ID | 6480 |
| Alias | Beta-galactoside alpha-2,6-sialyltransferase 1 (Alpha 2,6-ST 1),B-cell antigen CD75,CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1,ST6Gal I (ST6GalI),Sialyltransferase 1,ST6GAL1,SIAT1 |
| Background | Antibody anti-ST6GAL1 |
| Status | RUO |
| Note | Mol. Weight 50 kDa |
Descripción
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Human ST6GAL1 (Beta-galactoside alpha-2,6-sialyltransferase 1) ELISA Kit
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ST6GAL1 antibody
This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.
Ver ProductoST6GAL1 antibody
ST6GAL1 (β-galactoside α-2-6 sialyl transferase1; also known as ST6N or CD75) is a sialyltransferase mediating the glycosylation of proteins and lipids to form functionally important glycoproteins and glycolipids in the Golgi compartment. It is principally expressed in liver, placenta and skeletal muscle. ST6GAL1 undergoes proteolytic process to generate soluble form from membrane form. Western blot analysis of human liver using this antibody detects both isoforms between 43-50 kDa. Higher molecular weight of bands around 50-70 kDa can also be observed with unknown reason.
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