Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody

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260€ (50 µg)

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935106861
info@markelab.com
name
Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx377999
tested applications
ELISA, WB, IHC

Description

Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody is a Rabbit polyclonal antibody for the detection of Human Beta-Adrenergic Receptor Kinase 1 (GRK2).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Beta-Adrenergic Receptor Kinase 1 (GRK2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P25098
Gene ID
156
NCBI Accession
NP_001610.2
Background
Antibody anti-GRK2
Status
RUO

Descripción

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Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody

The product of this gene phosphorylates the beta 2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes.

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