Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody

383.5€ (100 µl)
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935106861
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name
Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx011687
tested applications
ELISA, WB, IHC, IF/ICC
Description
The product of this gene phosphorylates the beta 2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Beta-Adrenergic Receptor Kinase 1 (GRK2) |
Host | Mouse |
Reactivity | Human, Mouse, Rat, Monkey |
Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG1 |
Purification | Unpurified ascites. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, IF/ICC |
Buffer | Ascitic fluid containing 0.03% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P25098 |
Gene ID | 156 |
Background | Antibody anti-GRK2 |
Status | RUO |
Note | Concentration: Not determined. - |
Descripción
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Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody
The product of this gene phosphorylates the beta 2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes.
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