Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody

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383.5€ (100 µl)

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935106861
info@markelab.com
name
Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx011687
tested applications
ELISA, WB, IHC, IF/ICC

Description

The product of this gene phosphorylates the beta 2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Beta-Adrenergic Receptor Kinase 1 (GRK2)
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Recommended Dilution
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Purification
Unpurified ascites.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
Ascitic fluid containing 0.03% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P25098
Gene ID
156
Background
Antibody anti-GRK2
Status
RUO
Note
Concentration: Not determined. -

Descripción

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abx011687

Beta-Adrenergic Receptor Kinase 1 (GRK2) Antibody

The product of this gene phosphorylates the beta 2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes.

Ver Producto