Bcl-2-Like Protein 13 (BCL2L13) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Bcl-2-Like Protein 13 (BCL2L13) Antibody is a Rabbit polyclonal antibody for the detection of Human Bcl-2-Like Protein 13 (BCL2L13).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Bcl-2-Like Protein 13 (BCL2L13) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BXK5 |
| Gene ID | 23786 |
| NCBI Accession | NP_001257658.1 |
| Background | Antibody anti-BCL2L13 |
| Status | RUO |
Descripción
Related Products
Recombinant Human BCL2L13
Ver Producto
Bcl2 Like Protein 13 (BCL2L13) Antibody
BCL2L13 Antibody is a Rabbit Polyclonal antibody against BCL2L13. Apoptosis is defined as a set of cascades which, when initiated, program the cell to undergo lethal changes such as membrane blebbing, mitochondrial breakdown and DNA fragmentation. The Bcl-2 family of proteins plays a central regulatory role in apoptosis. Bcl-rambo, a member of the Bcl-2 family, localizes to the mitochondria and, like other Bcl-2 family members, contains all four BH domains. Although Bcl-rambo shares structural similarity to other Bcl-2 members, it differs from them in its unique C-terminal region. Bcl-rambo has a 250 amino acid sequence containing two tandem repeats that preceeds the membrane anchor region at its C-terminus. Additionally, it is the membrane anchor C-terminal region of Bcl-rambo, not its Bcl-2 homology motifs, that is responsible for its pro-apoptotic activity. Bcl-rambo induces apoptosis when overexpressed and appears to do so by promoting mitochondrial cyto-chrome c release. It may also facilitate the activation of caspase-3.
Ver Producto