BCL2L13 antibody
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Description
May promote the activation of caspase-3 and apoptosis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | BCL2-like 13(apoptosis facilitator) (BCL2L13) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:6000; IP: 1:500-1:3000; IHC: 1:50-1:500; IF: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 85kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BXK5 |
| Gene ID | 23786 |
| Alias | Bcl-2-like protein 13 (Bcl2-L-13),Bcl-rambo,Protein Mil1,BCL2L13,MIL1 |
| Background | Antibody anti-BCL2L13 |
| Status | RUO |
| Note | Mol. Weight 85 kDa |
Descripción
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Recombinant Human BCL2L13
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Bcl2 Like Protein 13 (BCL2L13) Antibody
BCL2L13 Antibody is a Rabbit Polyclonal antibody against BCL2L13. Apoptosis is defined as a set of cascades which, when initiated, program the cell to undergo lethal changes such as membrane blebbing, mitochondrial breakdown and DNA fragmentation. The Bcl-2 family of proteins plays a central regulatory role in apoptosis. Bcl-rambo, a member of the Bcl-2 family, localizes to the mitochondria and, like other Bcl-2 family members, contains all four BH domains. Although Bcl-rambo shares structural similarity to other Bcl-2 members, it differs from them in its unique C-terminal region. Bcl-rambo has a 250 amino acid sequence containing two tandem repeats that preceeds the membrane anchor region at its C-terminus. Additionally, it is the membrane anchor C-terminal region of Bcl-rambo, not its Bcl-2 homology motifs, that is responsible for its pro-apoptotic activity. Bcl-rambo induces apoptosis when overexpressed and appears to do so by promoting mitochondrial cyto-chrome c release. It may also facilitate the activation of caspase-3.
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