BAG Family Molecular Chaperone Regulator 2 (BAG2) Antibody

Documentos del producto

Especificaciones del producto

Primary Antibodies

Target: BAG Family Molecular Chaperone Regulator 2 (BAG2)

Mouse

Human

Monoclonal

5 µg

20 µg

100 µg

Shipped within 5-10 working days.

No

BAG-2,dJ417I1.2,Bcl-2-associated athanogene 2,BAG family molecular chaperone regulator 2

Antibody anti-BAG2

RUO

THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

BAG cochaperone 2 (BAG2) is a protein that functions as a cochaperone for heat shock proteins (HSPs), particularly HSP70, to regulate protein folding and degradation BAG2 plays a key role in controlling the cellular stress response by modulating protein homeostasis under stress conditions It interacts with misfolded proteins and assists in their proper folding or directs them for proteasomal degradation through the ubiquitin-proteasome pathway BAG2 also has roles in the regulation of apoptosis, where it can influence cell survival by interacting with pro-apoptotic factors BAG2 is implicated in various diseases, including cancer, where its expression can promote tumor progression by stabilizing key oncogenic proteins and inhibiting cell death pathways Additionally, BAG2 has been linked to neurodegenerative diseases such as Parkinson's disease, where its role in protein quality control is crucial for preventing the accumulation of toxic protein aggregates Its ability to modulate protein turnover and cell survival pathways highlights BAG2 as an important player in maintaining cellular integrity and a potential target for therapeutic intervention