B-Lymphocyte Antigen CD19 (CD19) Antibody (PE / Cyanine 5)
104€ (50 tests)
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Name
B-Lymphocyte Antigen CD19 (CD19) Antibody (PE / Cyanine 5)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx228008
Tested Applications
FCM
Description
CD19 antibody (PE / Cyanine 5) is a Rat monoclonal antibody against CD19.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: B-Lymphocyte Antigen CD19 (CD19) |
| Host | Rat |
| Reactivity | Mouse |
| Detection Method | Laser Line: 550 Excitation/Emission: 565/667 |
| Clonality | Monoclonal |
| Conjugation | PE / Cyanine 5 |
| Isotype | IgG2a |
| Size 1 | 50 tests |
| Size 2 | 25 µg |
| Size 3 | 100 tests |
| Size 4 | 100 µg |
| Size 5 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P25918 |
| Gene ID | 12478 |
| Alias | B4,CVID3,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12 |
| Background | Antibody anti-CD19 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD19 is a transmembrane glycoprotein primarily expressed on B cells, a subset of white blood cells responsible for producing antibodies and mediating humoral immunity. CD19 plays a crucial role in B-cell development, activation, and differentiation, making it a critical marker and regulator in the immune response. It is part of the immunoglobulin superfamily and serves as a coreceptor for the B-cell receptor (BCR), amplifying BCR-mediated signaling, which is essential for proper immune function. CD19 is expressed throughout most stages of B-cell development, from the pro-B cell stage in the bone marrow to mature B cells in peripheral tissues. This widespread expression makes it a reliable marker for identifying B cells in research and clinical settings, and it is often targeted in therapeutic strategies aimed at modulating B-cell function, such as in CAR-T cell therapy for treating B-cell malignancies.
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