B-Lymphocyte Antigen CD19 (CD19) Antibody (PE)

Este producto es parte de CD19 - CD19 molecule
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520€ (100 tests)

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935106861
info@markelab.com
name
B-Lymphocyte Antigen CD19 (CD19) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx413079
tested applications
FCM

Description

Cluster of Differentiation 19 (CD19) Antibody (PE) is a Rat Monoclonal antibody against Cluster of Differentiation 19 (CD19).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetB-Lymphocyte Antigen CD19 (CD19)
HostRat
ReactivityMouse
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConjugationPE
IsotypeIgG2a
PurificationPurified
Size 1100 tests
FormLyophilized
Tested ApplicationsFCM
BufferPBS, 1% BSA. Contains sodium azide.
AvailabilityShipped within 3-7 working days.
StorageStore at -20 °C or -80 °C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP25918
AliasB4,CVID3,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12
BackgroundAntibody anti-CD19
StatusRUO

Descripción

CD19 is a transmembrane glycoprotein primarily expressed on B cells, a subset of white blood cells responsible for producing antibodies and mediating humoral immunity. CD19 plays a crucial role in B-cell development, activation, and differentiation, making it a critical marker and regulator in the immune response. It is part of the immunoglobulin superfamily and serves as a coreceptor for the B-cell receptor (BCR), amplifying BCR-mediated signaling, which is essential for proper immune function. CD19 is expressed throughout most stages of B-cell development, from the pro-B cell stage in the bone marrow to mature B cells in peripheral tissues. This widespread expression makes it a reliable marker for identifying B cells in research and clinical settings, and it is often targeted in therapeutic strategies aimed at modulating B-cell function, such as in CAR-T cell therapy for treating B-cell malignancies.

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