B-Lymphocyte Antigen CD19 (CD19) Antibody (APC)

Este producto es parte de CD19 - CD19 molecule
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637€ (100 tests)

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935106861
info@markelab.com
name
B-Lymphocyte Antigen CD19 (CD19) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx270547
tested applications
FCM

Description

Cluster Of Differentiation 19 (CD19) Antibody (APC) is a Rabbit Polyclonal Antibody conjugated to APC against Cluster Of Differentiation 19 (CD19) for use in flow cytometry.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
B-Lymphocyte Antigen CD19 (CD19)
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
APC
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
100 tests
Size 2
200 tests
Size 3
500 tests
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light.
Dry Ice
No
Alias
B4,CVID3,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12
Background
Antibody anti-CD19
Status
RUO

Descripción

CD19 is a transmembrane glycoprotein primarily expressed on B cells, a subset of white blood cells responsible for producing antibodies and mediating humoral immunity. CD19 plays a crucial role in B-cell development, activation, and differentiation, making it a critical marker and regulator in the immune response. It is part of the immunoglobulin superfamily and serves as a coreceptor for the B-cell receptor (BCR), amplifying BCR-mediated signaling, which is essential for proper immune function. CD19 is expressed throughout most stages of B-cell development, from the pro-B cell stage in the bone marrow to mature B cells in peripheral tissues. This widespread expression makes it a reliable marker for identifying B cells in research and clinical settings, and it is often targeted in therapeutic strategies aimed at modulating B-cell function, such as in CAR-T cell therapy for treating B-cell malignancies.

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