B-Lymphocyte Antigen CD19 (CD19) Antibody
299€ (50 µl)
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935106861
info@markelab.com
name
B-Lymphocyte Antigen CD19 (CD19) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx402384
tested applications
ELISA, WB, IHC, IP
Description
B-Lymphocyte Antigen CD19 (CD19) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human CD19.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | B-Lymphocyte Antigen CD19 (CD19) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/50 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P15391 |
| NCBI Accession | NP_001171569.1, NP_001761.3 |
| Alias | B4,CVID3,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12 |
| Background | Antibody anti-CD19 |
| Status | RUO |
Descripción
CD19 is a transmembrane glycoprotein primarily expressed on B cells, a subset of white blood cells responsible for producing antibodies and mediating humoral immunity. CD19 plays a crucial role in B-cell development, activation, and differentiation, making it a critical marker and regulator in the immune response. It is part of the immunoglobulin superfamily and serves as a coreceptor for the B-cell receptor (BCR), amplifying BCR-mediated signaling, which is essential for proper immune function. CD19 is expressed throughout most stages of B-cell development, from the pro-B cell stage in the bone marrow to mature B cells in peripheral tissues. This widespread expression makes it a reliable marker for identifying B cells in research and clinical settings, and it is often targeted in therapeutic strategies aimed at modulating B-cell function, such as in CAR-T cell therapy for treating B-cell malignancies.
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