B-Lymphocyte Antigen CD19 (CD19) Antibody

Este producto es parte de CD19 - CD19 molecule
B-Lymphocyte Antigen CD19 (CD19) Antibody
286€ (50 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
B-Lymphocyte Antigen CD19 (CD19) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx270017
Tested Applications
FCM

Description

Cluster Of Differentiation 19 (CD19) Antibody is a Rabbit Polyclonal Antibody against Cluster Of Differentiation 19 (CD19) for use in flow cytometry.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: B-Lymphocyte Antigen CD19 (CD19)
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
50 tests
Size 2
100 tests
Size 3
200 tests
Size 4
500 tests
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
B4,CVID3,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12
Background
Antibody anti-CD19
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

CD19 is a transmembrane glycoprotein primarily expressed on B cells, a subset of white blood cells responsible for producing antibodies and mediating humoral immunity. CD19 plays a crucial role in B-cell development, activation, and differentiation, making it a critical marker and regulator in the immune response. It is part of the immunoglobulin superfamily and serves as a coreceptor for the B-cell receptor (BCR), amplifying BCR-mediated signaling, which is essential for proper immune function. CD19 is expressed throughout most stages of B-cell development, from the pro-B cell stage in the bone marrow to mature B cells in peripheral tissues. This widespread expression makes it a reliable marker for identifying B cells in research and clinical settings, and it is often targeted in therapeutic strategies aimed at modulating B-cell function, such as in CAR-T cell therapy for treating B-cell malignancies.

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