B-Cell Maturation Antigen Protein
234€ (5 µg)
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935106861
info@markelab.com
name
B-Cell Maturation Antigen Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262205
tested applications
SDS-PAGE
Description
B-Cell Maturation Antigen Protein is a recombinant cytokine.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | TNFRSF17 |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 98% (SDS-PAGE and RP-HPLC) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q02223 |
| Alias | Tumor necrosis factor receptor superfamily member 17,BCM,BCMA,CD269,TNFRSF13A,B-cell maturation protein |
| Background | Protein TNFRSF17 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity. TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity.
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