Autophagy Related 4B Cysteine Peptidase (ATG4B) Antibody

Product Graph
292.5€ (80 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Autophagy Related 4B Cysteine Peptidase (ATG4B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025271
tested applications
ELISA, WB

Description

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Autophagy Related 4B Cysteine Peptidase (ATG4B)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgM
Purification
Purified Mouse Monoclonal Antibody.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9Y4P1
Alias
APG4B,AUTL1,HsAPG4B
Background
Antibody anti-ATG4B
Status
RUO

Descripción

Related Products

FNab00674

ATG4B antibody

Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Ver Producto
P7060

Recombinant Human ATG4B

Ver Producto
abx006179

Autophagy Related 4B Cysteine Peptidase (ATG4B) Antibody

ATG4B Antibody is a Rabbit Polyclonal Antibody against ATG4B.

Ver Producto