ATP/GTP Binding Protein Like 1 (AGBL1) Antibody

357.5€ (100 µg)
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935106861
info@markelab.com
name
ATP/GTP Binding Protein Like 1 (AGBL1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037592
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the AGBL1 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | ATP/GTP Binding Protein Like 1 (AGBL1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by antigen affinity column chromatography. |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Lyophilized |
Tested Applications | ELISA, WB, IHC |
Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
Availability | Shipped within 7-15 working days. |
Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
NCBI Accession | NM_152336.2 |
Alias | CCP4,FECD8 |
Background | Antibody anti-AGBL1 |
Status | RUO |
Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
AGBL1 is a member of the AGBL (ATP/GTP-binding protein-like) carboxypeptidase family, which functions in the post-translational modification of tubulin. Specifically, AGBL1 participates in the removal of polyglutamate chains from the C-terminal tails of tubulin, regulating microtubule stability and cytoskeletal dynamics. AGBL1 is widely expressed, including in neuronal tissues and cardiovascular systems, where it influences axon guidance, neuroplasticity, and cardiac function. Dysregulation of AGBL1 has been implicated in conditions such as retinal dystrophy and cardiovascular diseases, highlighting its role in maintaining microtubule-dependent processes critical for cellular transport and structural integrity.
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