ATPase, Na+/K+ Transporting Beta 1 Polypeptide (ATP1B1) Antibody

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Description
ATP1B1 Antibody is a Rabbit Polyclonal antibody against ATP1B1. The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | ATPase, Na+/K+ Transporting Beta 1 Polypeptide (ATP1B1) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | IHC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P05026 |
Gene ID | 481 |
NCBI Accession | NP_001668.1 |
Alias | ATP1B,Sodium/potassium-dependent ATPase subunit beta-1 |
Background | Antibody anti-ATP1B1 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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