ATP-Dependent 6-Phosphofructokinase, Muscle Type (PFKM) Antibody (FITC)

169€ (20 µg)
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935106861
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name
ATP-Dependent 6-Phosphofructokinase, Muscle Type (PFKM) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx314270
Description
PFKM Antibody (FITC) is a Rabbit Polyclonal against PFKM conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | ATP-Dependent 6-Phosphofructokinase, Muscle Type (PFKM) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | FITC |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P08237 |
Gene ID | 5213 |
NCBI Accession | NP_000280.1, NM_000289.5 |
OMIM | 232800 |
Background | Antibody anti-PFKM |
Status | RUO |
Descripción
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Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
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