PFKM antibody

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935106861
info@markelab.com
name
PFKM antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06341
tested applications
ELISA, WB, IHC
Description
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | phosphofructokinase, muscle (PFKM) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 85 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | P08237 |
Gene ID | 5213 |
Alias | ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK, PFK-M),6-phosphofructokinase type A,Phosphofructo-1-kinase isozyme A (PFK-A),Phosphohexokinase,PFKM,PFKX |
Background | Antibody anti-PFKM |
Status | RUO |
Note | Mol. Weight 85 kDa |
Descripción
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PFKM antibody
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Ver Producto