ATP Binding Cassette Transporter A13 (ABCA13) Antibody

Este producto es parte de ABCA13 - ATP Binding Cassette Transporter A13
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357.5€ (100 µg)

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935106861
info@markelab.com
name
ATP Binding Cassette Transporter A13 (ABCA13) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037596
tested applications
ELISA, IHC

Description

Rabbit Polyclonal against the ABCA13 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
ATP Binding Cassette Transporter A13 (ABCA13)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, IHC
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NM_152701
Alias
ATP-binding cassettE sub-family A (ABC1) member 13
Background
Antibody anti-ABCA13
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

ABCA13 (ATP-binding cassette subfamily A member 13) is a member of the ATP-binding cassette (ABC) transporter superfamily, a large group of proteins that facilitate the transport of various substrates across cellular membranes. ABCA13, encoded by the ABCA13 gene on chromosome 7p12, is the largest known ABC transporter, with a coding sequence of over 5000 amino acids. Although the precise substrates transported by ABCA13 remain to be fully elucidated, its expression in neural and psychiatric contexts has drawn attention to its potential role in the central nervous system. Emerging studies suggest its involvement in lipid transport, vesicle trafficking, and membrane organization. ABCA13 is predominantly expressed in the brain, particularly in regions associated with neural activity, such as the hippocampus, cortex, and striatum. It has also been detected in other tissues, including the lungs and liver, albeit at lower levels. Dysregulation of ABCA13 has been implicated in neuropsychiatric conditions, such as schizophrenia, bipolar disorder, and depression.

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