ATP Binding Cassette Subfamily G Member 4 (ABCG4) Antibody

Background

ABCG4 is a member of the ATP-binding cassette (ABC) transporter family, subfamily G, primarily expressed in the brain, macrophages, and hematopoietic stem cells. This protein plays a key role in cellular lipid homeostasis, particularly in cholesterol and phospholipid transport. It is involved in maintaining membrane lipid composition and may contribute to processes like neuroprotection and immune cell function. Dysfunction or aberrant regulation of ABCG4 is implicated in lipid-related disorders and neurological diseases. Understanding its precise role is critical for exploring its therapeutic potential in metabolic and neurodegenerative conditions.