ATP Binding Cassette Subfamily F Member 3 (ABCF3) Antibody

Este producto es parte de ABCF - ATP Binding Cassette Transporter F
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273€ (200 µl)

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935106861
info@markelab.com
name
ATP Binding Cassette Subfamily F Member 3 (ABCF3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431873
tested applications
P-ELISA

Description

ABCF3 Antibody is a Goat Polyclonal antibody against ABCF3.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
ATP Binding Cassette Subfamily F Member 3 (ABCF3)
Host
Goat
Recommended Dilution
P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
55324, 27406, 287982
NCBI Accession
NP_060828.2
Alias
EST201864
Background
Antibody anti-ABCF3
Status
RUO
Note
Concentration: 0.5 mg/ml - 

Descripción

ABCF3 is a member of the ABCF subfamily, characterized by its lack of transmembrane domains and its involvement in intracellular processes such as translation regulation and stress response. It is expressed in various tissues, with functions related to ribosomal activity and protein synthesis. ABCF3 is believed to play a role in modulating the translation machinery, particularly under conditions of cellular stress, enabling cells to adapt to adverse environments by selectively synthesizing stress-related proteins. Its role in maintaining protein synthesis is essential for cell survival during environmental challenges, such as oxidative stress or nutrient deprivation. Dysregulation of ABCF3 has been associated with impaired stress tolerance and altered protein homeostasis, which can contribute to pathological conditions such as neurodegenerative diseases or cancer. While its exact molecular mechanisms remain under investigation, ABCF3’s contribution to translation regulation and cellular adaptation highlights its critical role in maintaining cellular integrity and function under both normal and stress conditions.

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