ATP-Binding Cassette Subfamily B Member 9 (ABCB9) Antibody
442€ (200 µl)
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935106861
info@markelab.com
name
ATP-Binding Cassette Subfamily B Member 9 (ABCB9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430473
tested applications
P-ELISA, IHC
Description
ABCB9 Antibody is a Goat Polyclonal antibody against ABCB9.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: ATP-Binding Cassette Subfamily B Member 9 (ABCB9) Immunogen: abx269268 - C-Terminus: C-GHNEPVANGSHKA |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 23457 |
| NCBI Accession | NP_062570.1, NP_062571.1, NP_982269.1 |
| Alias | EST122234,TAPL |
| Background | Antibody anti-ABCB9 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ABCB9, also known as TAPL (Transporter Associated with Antigen Processing-Like), is an ATP-binding cassette transporter localized to lysosomes and late endosomes. It plays a role in the transport of peptides into lysosomal compartments, contributing to processes such as antigen presentation and lysosomal proteostasis. ABCB9 contains two nucleotide-binding domains and transmembrane regions that mediate ATP-dependent peptide transport. It is expressed in various tissues, with higher levels in immune-related cells, where it supports lysosomal function and immune responses. Although its precise physiological substrates and roles remain under investigation, ABCB9’s involvement in lysosomal function underscores its importance in cellular homeostasis, immune regulation, and protein degradation pathways.
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