AT1A, Angiotensin II receptor, Peptide
351€ (5 mg)
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935106861
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name
AT1A, Angiotensin II receptor, Peptide
category
Proteins and Peptides
provider
Abbexa
reference
abx266391
Description
AT1A, Angiotensin II receptor, (225 - 237) is a peptide.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | AT1A, Angiotensin II receptor, (225 237) |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: 1590.73 Da Sequence Fragment: 225-237 AA |
| Purity | > 95% (HPLC) |
| Size 1 | 5 mg |
| Size 2 | 10 mg |
| Size 3 | 25 mg |
| Form | Lyophilized |
| Buffer | Not applicable. |
| Availability | Shipped within 10-20 working days. |
| Storage | Store dry at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor |
| Background | Protein AGTR1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.
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