Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody

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312€ (60 µl)

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935106861
info@markelab.com
name
Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx000925
tested applications
WB

Description

ARNT Antibody is a Rabbit Polyclonal antibody against ARNT. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.

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Product specifications

CategoryPrimary Antibodies
Immunogen TargetAryl Hydrocarbon Receptor Nuclear Translocator (ARNT)
HostRabbit
ReactivityHuman, Mouse, Rat
Recommended DilutionWB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified by affinity chromatography.
Size 160 µl
Size 2120 µl
Size 3200 µl
FormLiquid
Tested ApplicationsWB
BufferPBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP27540
Gene ID405
NCBI AccessionNP_001659.1
AliasARNT,BHLHE2,Dioxin receptor, nuclear translocator
BackgroundAntibody anti-ARNT
StatusRUO
NoteConcentration: 1 mg/ml -

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