Aryl Hydrocarbon Receptor (AHR) Antibody
260€ (50 µg)
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name
Aryl Hydrocarbon Receptor (AHR) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx455242
tested applications
ELISA, WB, IHC
Description
Aryl Hydrocarbon Receptor (AHR) Antibody is a Rabbit polyclonal antibody for the detection of Human Aryl Hydrocarbon Receptor (AHR).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Aryl Hydrocarbon Receptor (AHR) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to 2 weeks. For long-term storage, aliquot and store at -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P35869 |
| Gene ID | 196 |
| NCBI Accession | NP_001612.1 |
| Alias | RP85,bHLHe76 |
| Background | Antibody anti-AHR |
| Status | RUO |
Descripción
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AHR antibody
Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
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