Actin-Related Protein 8 (ACTR8) Antibody (FITC)
169€ (20 µg)
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935106861
info@markelab.com
name
Actin-Related Protein 8 (ACTR8) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx311204
Description
ACTR8 Antibody (FITC) is a Rabbit Polyclonal against ACTR8 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin-Related Protein 8 (ACTR8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H981 |
| Gene ID | 93973 |
| NCBI Accession | NP_075050.3, NM_022899.4 |
| Alias | ARP8,INO80N |
| Background | Antibody anti-ACTR8 |
| Status | RUO |
Descripción
ACTR8, also known as ARP8, is a nuclear actin-related protein that functions within the INO80 chromatin remodeling complex. It plays a critical role in ATP-dependent nucleosome remodeling, facilitating DNA repair, replication, and transcriptional regulation. Structurally, ACTR8 resembles actin but interacts specifically with chromatin and ATPase subunits. ACTR8 is vital for genomic stability, particularly in response to DNA double-strand breaks. Dysregulation of ACTR8 impairs chromatin organization and has been implicated in tumorigenesis and other genomic disorders.
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