Archaelysin Family Metallopeptidase 1 (AMZ1) Antibody
364€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Archaelysin Family Metallopeptidase 1 (AMZ1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230385
tested applications
ELISA, WB, IHC, IF/ICC
Description
AMZ1 Antibody is a Rabbit Polyclonal against AMZ1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Archaelysin Family Metallopeptidase 1 (AMZ1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/20 - 1/200, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q400G9 |
| Gene ID | 155185 |
| OMIM | 615168 |
| Alias | AMZ1 |
| Background | Antibody anti-AMZ1 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
AMZ1 is a member of the archaelysin family of zinc-dependent metallopeptidases, enzymes that cleave peptide bonds in a variety of substrates. AMZ1 is expressed in multiple tissues, where it functions in protein turnover, extracellular matrix remodeling, and cellular signaling. As a metallopeptidase, AMZ1 requires a zinc ion for catalytic activity, which stabilizes the enzyme's active site and facilitates hydrolysis of peptide bonds. AMZ1 is thought to participate in processes such as tissue development, wound healing, and immune responses by regulating extracellular matrix components and growth factors. Dysregulation of AMZ1 activity has been implicated in pathological processes such as fibrosis, inflammation, and tumor progression, where excessive matrix degradation or improper protease activity contributes to disease. AMZ1's ability to cleave a broad range of substrates highlights its importance in maintaining proteolytic balance, tissue homeostasis, and intercellular communication.
Related Products
AMZ1 antibody
AMZ1, also named as KIAA1950, is a new human Zinc metalloproteases. It exhibits aminopeptidase activity against neurogranin in vitro. AMZ1 does not hydrolyze angiotensin-2. It is mainly detected in liver and heart. AMZ1 has some isoforms with MW 55 kDa, 33 kDa, 30 kDa and 28 kDa.
Ver Producto