Amyloid-beta Precursor Protein (APP) Peptide

Este producto es parte de APP - Beta-Amyloid Precursor Protein
Amyloid-beta Precursor Protein (APP) Peptide
221€ (5 mg)

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Name
Amyloid-beta Precursor Protein (APP) Peptide
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx265758

Description

Beta-Amyloid/A4 Protein Precursor (APP) (328 - 332) is a peptide.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Amyloid-beta Precursor Protein (APP)
Assay Type
Sequence Fragment: 328-332 AA.
Conjugation
Unconjugated
Observed MW
677.79 Da
Purity
> 95% (HPLC)
Size 1
5 mg
Size 2
10 mg
Size 3
25 mg
Form
Lyophilized
Buffer
Not applicable.
Availability
Shipped within 10-20 working days.
Storage
Store dry at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein
Background
Protein APP
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

APP is a transmembrane glycoprotein widely expressed in the brain and peripheral tissues that plays a critical role in neuronal development, synaptic plasticity, and cell adhesion APP is proteolytically processed by enzymes such as α-secretase, β-secretase, and γ-secretase, leading to the production of various fragments, including the beta-amyloid (Aβ) peptide Abnormal processing of APP and the accumulation of Aβ peptides form amyloid plaques, which are a hallmark of Alzheimer’s disease and contribute to neurotoxicity and neurodegeneration APP also interacts with various proteins to mediate intracellular signaling and cellular responses Mutations in the APP gene are associated with early-onset familial Alzheimer’s disease, highlighting its role in the pathogenesis of neurodegenerative disorders

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