APP (pT743) Antibody is a Rabbit Polyclonal antibody against APP (pT743). This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Primary Antibodies
Polyclonal
Mouse, Rat
Beta-Amyloid Precursor Protein Phospho-Thr743 (APP pT743)
Rabbit
Unconjugated
Liquid
WB
Purified by affinity chromatography.
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
20 µl
50 µl
100 µl
200 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
APP
No
Shipped within 5-10 working days.
AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein
NP_958817.1
This product is for research use only.
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