Apoptosis Antagonizing Transcription Factor (AATF) Antibody (HRP)
169€ (20 µg)
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Name
Apoptosis Antagonizing Transcription Factor (AATF) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx108651
Tested Applications
ELISA
Description
Protein AATF Antibody (HRP) is a Rabbit Polyclonal antibody against Protein AATF conjugated to HRP.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Apoptosis Antagonizing Transcription Factor (AATF) Immunogen: Recombinant human Protein AATF protein (6-294AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NY61 |
| Gene ID | 26574 |
| OMIM | 608463 |
| Alias | DED,BFR2,CHE1,CHE-1 |
| Background | Antibody anti-AATF |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AATF (Apoptosis Antagonizing Transcription Factor), also known as Che-1, is a transcription factor involved in various cellular processes, including the regulation of apoptosis, cell cycle progression, and DNA damage response. It acts as a survival factor by inhibiting apoptotic pathways and promoting cell proliferation and survival.It also interacts directly with nuclear hormone receptors to enhance their transactivation. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis
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