Apolipoprotein L2 (APOL2) Antibody

Este producto es parte de APOL2 - Apolipoprotein L2
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364€ (100 µg)

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935106861
info@markelab.com
name
Apolipoprotein L2 (APOL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230504
tested applications
ELISA, WB, IHC

Description

APOL2 Antibody is a Rabbit Polyclonal against APOL2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Apolipoprotein L2 (APOL2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9BQE5
Gene ID
23780
OMIM
607252
Alias
APOL2, APOL-II, APOL3, apolipoprotein L2,APO L2
Background
Antibody anti-APOL2
Status
RUO
Note
Concentration: 2 mg/ml - Validity: 12 months.

Descripción

Apolipoprotein L2 (APOL2) is another member of the Apolipoprotein L family and is involved in lipid metabolism, cellular transport, and immune responses. APOL2 is expressed in various tissues, including the brain, liver, and immune cells, and interacts with intracellular membranes and lipid-containing structures. While its function is less defined than APOL1, APOL2 is believed to participate in lipid transport and the regulation of cellular lipid balance. Recent research has suggested that APOL2 may play a role in the modulation of apoptosis, cellular survival, and responses to oxidative stress. Its expression levels are often altered in disease states such as cancers and neurodegenerative disorders, where APOL2 may contribute to tumor progression, inflammation, and immune regulation. Studies also suggest a connection between APOL2 and host-pathogen interactions, as its upregulation has been observed in response to infections and inflammatory cytokines. APOL2’s involvement in cellular homeostasis, combined with its emerging roles in immune response and lipid handling, makes it a promising target for further research into its function and potential therapeutic applications in cancer and immune-mediated diseases.

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