Apolipoprotein A4 (APOA4) Antibody

Este producto es parte de APOA4 - Apolipoprotein A4
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312€ (100 µl)

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935106861
info@markelab.com
name
Apolipoprotein A4 (APOA4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx131730
tested applications
WB, IHC, IF/ICC

Description

Apolipoprotein A4 Antibody is a Mouse Monoclonal against Apolipoprotein A4.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Apolipoprotein A4 (APOA4)
Host
Mouse
Reactivity
Pig
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG2b Kappa
Purification
Purified by Protein A and Protein G affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O46409
Alias
APOA4, apolipoprotein A4, APO A4,APO A-4,apoA-IV,apoAIV,apoA4,Apolipoprotein A-IV
Background
Antibody anti-APOA4
Status
RUO

Descripción

APOA4 is a protein primarily synthesized in the small intestine and secreted into the bloodstream as a component of chylomicrons during dietary fat absorption. It plays a key role in lipid metabolism, facilitating the transport and metabolism of triglycerides and cholesterol. APOA4 has been shown to activate lecithin-cholesterol acyltransferase (LCAT), promoting cholesterol esterification and contributing to reverse cholesterol transport. Additionally, APOA4 exhibits anti-inflammatory and antioxidant properties, protecting against atherosclerosis and cardiovascular diseases. It also regulates satiety by interacting with receptors in the hypothalamus, contributing to appetite control and energy balance. Elevated APOA4 levels are associated with improved lipid profiles, while its deficiency can impair lipid transport and metabolism.

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