Antizyme Inhibitor 1 (AZIN1) Antibody

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312€ (60 µl)

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935106861
info@markelab.com
name
Antizyme Inhibitor 1 (AZIN1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx003585
tested applications
WB

Description

AZIN1 Antibody is a Rabbit Polyclonal antibody against AZIN1. Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Antizyme Inhibitor 1 (AZIN1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
WB
Buffer
PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O14977
Gene ID
51582
NCBI Accession
NP_056962.2
Alias
OAZI,OAZIN,Ornithine decarboxylase antizyme inhibitor
Background
Antibody anti-AZIN1
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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AZIN1(Antizyme inhibitor 1) is also named as OAZI, OAZIN and belongs to the Orn/Lys/Arg decarboxylase class-II family. It catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis, and playing a role in the regulation of polyamine synthesis(negative regulator of cellular polyamines).

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Antizyme Inhibitor 1 (AZIN1) Antibody

AZIN1 Antibody is a Rabbit Polyclonal antibody against AZIN1. Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene.

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