Antigen Peptide Transporter 2 (TAP2) Antibody
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Description
TAP2 Antibody is a Rabbit Polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Jul 2008].
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Antigen Peptide Transporter 2 (TAP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q03519 |
| Gene ID | 6891 |
| NCBI Accession | NP_001276972.1 |
| Background | Antibody anti-TAP2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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TAP2 antibody
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Antigen Peptide Transporter 2 (TAP2) Antibody
TAP2 Antibody is a Rabbit Polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Jul 2008].
Ver Producto
Antigen Peptide Transporter 2 (TAP2) Antibody
TAP2 Antibody is a Rabbit Polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transportersABC proteins transport various molecules across extra- and intra-cellular membranesABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)This protein is a member of the MDR/TAP subfamilyMembers of the MDR/TAP subfamily are involved in multidrug resistanceThis gene is located 7 kb telomeric to gene family member ABCB2The protein encoded by this gene is involved in antigen presentationThis protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulumMutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac diseaseAlternative splicing of this gene produces two products which differ in peptide selectivity and level of restoRation of surface expression of MHC class I molecules.
Ver Producto