SLC39A8 antibody

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935106861
info@markelab.com
name
SLC39A8 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09643
tested applications
ELISA, WB, IHC, IF, IP

Description

SLC39A8 also known as ZIP8 belongs to the ZIP family of metal ion transporters which function to transport zinc and/or other metal ion substrates from the extracellular space or organellar lumen into the cytoplasm. Recently it was found that Zip8 expression is upregulated in human monocytes in response to LPS, TNF-α, and live bacteria, facilitating cytoprotection during the early inflammation. Besides zinc ZIP8 can also transport cadmium and manganese efficiently. It is predicted that ZIP8 contains 3 potential N-linked glycosylation sites and is subject to glycosylation, which may account for the presences of multiple molecular weights, such as 43 kDa, 49 kDa, 60 kDa, 75-90 kDa, 150 kDa, and 200 kDa.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
solute carrier family 39(zinc transporter), member 8 (SLC39A8)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
53 kDa, 75-90 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9C0K1
Gene ID
64116
Alias
Metal cation symporter ZIP8,BCG-induced integral membrane protein in monocyte clone 103 protein,LIV-1 subfamily of ZIP zinc transporter 6 (LZT-Hs6),Solute carrier family 39 member 8,Zrt- and Irt-like protein 8 (ZIP-8),SLC39A8,BIGM103,ZIP8
Background
Antibody anti-SLC39A8
Status
RUO
Note
Mol. Weight 53 kDa, 75-90 kDa

Descripción

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