ZGPAT antibody
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935106861
info@markelab.com
name
ZGPAT antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09634
tested applications
ELISA, WB
Description
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | zinc finger, CCCH-type with G patch domain (ZGPAT) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:5000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 57 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N5A5 |
| Gene ID | 84619 |
| Alias | Zinc finger CCCH-type with G patch domain-containing protein,G patch domain-containing protein 6,Zinc finger CCCH domain-containing protein 9,Zinc finger and G patch domain-containing protein,ZGPAT,GPATC6,GPATCH6,KIAA1847,ZC3H9,ZC3HDC9,ZIP |
| Background | Antibody anti-ZGPAT |
| Status | RUO |
| Note | Mol. Weight 57 kDa |
Descripción
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