anti- ZC3HC1 antibody

anti- ZC3HC1 antibody

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-ZC3HC1

proveedor

FineTest

reference

FNab09608

Tested Applications

ELISA, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1(CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

zinc finger, C3HC-type containing 1


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB


observerd MW

55 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:200-1:2000


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

ZC3HC1


alias

ZC3HC1, 1110054L24Rik, hNIPA, HSPC216, NIPA


note

This product is for research use only.


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