anti- ZC3H8 antibody

Descripción

Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region(IRR) of the GATA3 gene(By similarity). Component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Características del producto

clonality

polyclonal

reactivity

human

immunogen target

zinc finger CCCH-type containing 8

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB

observerd MW

34 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:1000-1:10000

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

ZC3H8

alias

Fliz1, ZC3H8, ZC3HDC8

uniprot id

https://www.uniprot.org/uniprotkb/Q8N5P1

gene id

https://www.ncbi.nlm.nih.gov/gene/84524

note

This product is for research use only.

Quizá le pueda interesar