anti- XRCC5/Ku80 antibody

Descripción

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Características del producto

clonality

polyclonal

reactivity

human

immunogen target

X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC

observerd MW

Refer to figures

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

or code

XRCC5/Ku80

alias

86 kDa subunit of Ku antigen, CTC85, CTCBF, DNA repair protein XRCC5, FLJ39089, G22P2, KARP 1, KARP1, Ku80, Ku86, KUB2, NFIV, Nuclear factor IV, Thyroid lupus autoantigen, TLAA, XRCC5

uniprot id

https://www.uniprot.org/uniprotkb/P13010

gene id

https://www.ncbi.nlm.nih.gov/gene/7520

note

This product is for research use only.

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Human XRCC5/Ku80(X-ray repair cross-complementing protein 5) ELISA Kit

proveedor

FineTest

reference

EH13689

reactivity

human

status

RUO

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