WWOX antibody
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935106861
info@markelab.com
name
WWOX antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09533
tested applications
ELISA, WB
Description
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development(By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor(TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | WW domain containing oxidoreductase (WWOX) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 47 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NZC7 |
| Gene ID | 51741 |
| Alias | WW domain-containing oxidoreductase,Fragile site FRA16D oxidoreductase,Short chain dehydrogenase/reductase family 41C member 1,WWOX,FOR,SDR41C1,WOX1 |
| Background | Antibody anti-WWOX |
| Status | RUO |
| Note | Mol. Weight 47 kDa |
Descripción
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