WDR24 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | WD repeat domain 24 (WDR24) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 102 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96S15 |
| Gene ID | 84219 |
| Alias | GATOR2 complex protein WDR24,WD repeat-containing protein 24,WDR24,C16orf21 |
| Background | Antibody anti-WDR24 |
| Status | RUO |
| Note | Mol. Weight 102 kDa |
Descripción
Related Products
WDR24 antibody
As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).
Ver Producto
WD Repeat-Containing Protein 24 (WDR24) Antibody
Rabbit Polyclonal against the WDR24 protein.
Ver ProductoWd Repeat Domain 24 (WDR24) Antibody
Wd Repeat Domain 24 Antibody is a Rabbit Polyclonal antibody against Wd Repeat Domain 24.
Ver Producto