VTA1 antibody
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Description
Involved in the endosomal multivesicular bodies(MVB) pathway. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR(By similarity). Involved in HIV-1 budding.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vps20-associated 1 homolog (VTA1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:10000;IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NP79 |
| Gene ID | 51534 |
| Alias | Vacuolar protein sorting-associated protein VTA1 homolog,Dopamine-responsive gene 1 protein (DRG-1),LYST-interacting protein 5 (LIP5),SKD1-binding protein 1 (SBP1),VTA1,C6orf55 |
| Background | Antibody anti-VTA1 |
| Status | RUO |
| Note | Mol. Weight 45 kDa |
Descripción
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