VPS8 antibody
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Description
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes(PubMed:25266290).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | vacuolar protein sorting 8 homolog (VPS8) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000;IP: 1:200-1:2000; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 151 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF,IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N3P4 |
| Gene ID | 23355 |
| Alias | Vacuolar protein sorting-associated protein 8 homolog,VPS8,KIAA0804 |
| Background | Antibody anti-VPS8 |
| Status | RUO |
| Note | Mol. Weight 151 kDa |
Descripción
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