VPS37A antibody
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Description
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | vacuolar protein sorting 37 homolog A (VPS37A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 44 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8NEZ2 |
| Gene ID | 137492 |
| Alias | Vacuolar protein sorting-associated protein 37A (hVps37A),ESCRT-I complex subunit VPS37A,Hepatocellular carcinoma-related protein 1,VPS37A,HCRP1 |
| Background | Antibody anti-VPS37A |
| Status | RUO |
| Note | Mol. Weight 44 kDa |
Descripción
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