USP18 antibody
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935106861
info@markelab.com
name
USP18 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09313
tested applications
ELISA, WB
Description
Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms. Isoform 2: Has enzymatic activity similar to isoform 1 and interferes with type I interferon signaling. Major deISGylation enzyme for nuclear proteins(PubMed:22170061).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ubiquitin specific peptidase 18 (USP18) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70 kDa, 43 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UMW8 |
| Gene ID | 11274 |
| Alias | Ubl carboxyl-terminal hydrolase 18,43 kDa ISG15-specific protease (hUBP43),ISG15-specific-processing protease,Ubl thioesterase 18,USP18,ISG43 |
| Background | Antibody anti-USP18 |
| Status | RUO |
| Note | Mol. Weight 70 kDa, 43 kDa |
Descripción
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Human USP18 (Ubiquitin Specific Peptidase18) ELISA Kit
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USP18 antibody
Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms. Isoform 2: Has enzymatic activity similar to isoform 1 and interferes with type I interferon signaling. Major deISGylation enzyme for nuclear proteins(PubMed:22170061).
Ver Producto