UBE2B antibody
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Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ubiquitin-conjugating enzyme E2B (RAD6 homolog) (UBE2B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 16 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P63146 |
| Gene ID | 7320 |
| Alias | Ubiquitin-conjugating enzyme E2 B,E2 ubiquitin-conjugating enzyme B,RAD6 homolog B (HR6B, hHR6B),Ubiquitin carrier protein B,Ubiquitin-conjugating enzyme E2-17 kDa,Ubiquitin-protein ligase B,UBE2B,RAD6B,UBCH1 |
| Background | Antibody anti-UBE2B |
| Status | RUO |
| Note | Mol. Weight 16 kDa |
Descripción
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