UBE2A antibody

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935106861
info@markelab.com
name
UBE2A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09163
tested applications
ELISA, WB, IHC
Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | ubiquitin-conjugating enzyme E2A (RAD6 homolog) (UBE2A) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | Refer to figures |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | P49459 |
Gene ID | 7319 |
Alias | Ubiquitin-conjugating enzyme E2 A,E2 ubiquitin-conjugating enzyme A,RAD6 homolog A (HR6A, hHR6A),Ubiquitin carrier protein A,Ubiquitin-protein ligase A,UBE2A,RAD6A |
Background | Antibody anti-UBE2A |
Status | RUO |
Note | Mol. Weight 17 kDa |
Descripción
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UBE2A antibody
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.
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