TXNRD1 antibody
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935106861
info@markelab.com
name
TXNRD1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09133
tested applications
ELISA, WB, IHC, IF, FC, IP
Description
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | thioredoxin reductase 1 (TXNRD1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 54 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, FC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q16881 |
| Gene ID | 7296 |
| Alias | Thioredoxin reductase 1, cytoplasmic (TR),Gene associated with retinoic and interferon-induced mortality 12 protein (GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein),KM-102-derived reductase-like factor,Peroxidase TXNRD1,Thioredoxin reductase TR1,TXNRD1,GRIM12,KDRF |
| Background | Antibody anti-TXNRD1 |
| Status | RUO |
| Note | Mol. Weight 54 kDa |
Descripción
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Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
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