TWSG1 antibody
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935106861
info@markelab.com
name
TWSG1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09120
tested applications
ELISA, IHC, WB
Description
May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | twisted gastrulation homolog 1 (TWSG1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 35 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9GZX9 |
| Gene ID | 57045 |
| Alias | Twisted gastrulation protein homolog 1,TWSG1,TSG |
| Background | Antibody anti-TWSG1 |
| Status | RUO |
| Note | Mol. Weight 35 kDa |
Descripción
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