TDP2 antibody
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935106861
info@markelab.com
name
TDP2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09098
tested applications
ELISA, WB, IP
Description
TTRAP is a 5-prime tyrosyl-DNA phosphodiesterase that is required for efficient repair of topoisomerase II-induced DNA double-strand breaks. Thus it can remove lots of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, generating a free 5' phosphate to DNA. It also has 3'-tyrosyl DNA phophodiesterase activity, but not so efficient as TDP1. TTRAP functions as a negative regulator of ETS1 and inhibit nuclear factor-kappa-B activation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TRAF and TNF receptor associated protein (TDP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 44 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95551 |
| Alias | Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2, hTDP2),5'-tyrosyl-DNA phosphodiesterase (5'-Tyr-DNA phosphodiesterase),ETS1-associated protein 2,ETS1-associated protein II (EAPII),TRAF and TNF receptor-associated protein,Tyrosyl-RNA phosphodiesterase,VPg unlinkase,TDP2,EAP2,TTRAP |
| Background | Antibody anti-TDP2 |
| Status | RUO |
| Note | Mol. Weight 44 kDa |
Descripción
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TTRAP is a 5-prime tyrosyl-DNA phosphodiesterase that is required for efficient repair of topoisomerase II-induced DNA double-strand breaks. Thus it can remove lots of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, generating a free 5' phosphate to DNA. It also has 3'-tyrosyl DNA phophodiesterase activity, but not so efficient as TDP1. TTRAP functions as a negative regulator of ETS1 and inhibit nuclear factor-kappa-B activation.
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