TTK antibody

Product Graph
Contáctenos para saber el precio

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
TTK antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09094
tested applications
ELISA, WB, IHC

Description

Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity(via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

Documents del producto

Instrucciones
Descargar
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
TTK protein kinase (TTK)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
97 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P33981
Gene ID
7272
Alias
Dual specificity protein kinase TTK,Phosphotyrosine picked threonine-protein kinase (PYT),TTK,MPS1,MPS1L1
Background
Antibody anti-TTK
Status
RUO
Note
Mol. Weight 97 kDa

Descripción

Related Products

FNab09094

TTK antibody

Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity(via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

Ver Producto
abx001944

Dual Specificity Protein Kinase TTK (TTK) Antibody

TTK Antibody is a Rabbit Polyclonal antibody against TTK. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

Ver Producto
abx012940

Dual Specificity Protein Kinase TTK (TTK) Antibody

Rabbit polyclonal antibody against TTK protein. Immunogen region is C-terminal.

Ver Producto